Comments on: Welcome to Genes and Drugs http://talk.genesanddrugs.com/2006/07/20/hello-world/ Medicine Is Not One-Size-Fits-All Sun, 23 Nov 2008 14:04:39 +0000 http://wordpress.org/?v=2.0.2 by: Jason Bobe http://talk.genesanddrugs.com/2006/07/20/hello-world/#comment-6 Fri, 21 Jul 2006 17:22:06 +0000 http://talk.genesanddrugs.com/2006/07/20/hello-world/#comment-6 Great to see you've got the blog up and running! I hope you find blogging as gratifying as many of your other writing endeavors. Good luck! Great to see you’ve got the blog up and running! I hope you find blogging as gratifying as many of your other writing endeavors. Good luck!

]]> by: doctore http://talk.genesanddrugs.com/2006/07/20/hello-world/#comment-5 Thu, 20 Jul 2006 18:55:02 +0000 http://talk.genesanddrugs.com/2006/07/20/hello-world/#comment-5 Many publications about genetic medicine use the terms Pharmocogenetics (PGX) and Pharmacogenomics--sometimes interchangably. What’s the Difference? The short answer is that not everyone agrees on the distinction. PGX came first and is generally understood to be the branch of pharmacology that studies individual genetically defined or modified responses to medications. The methodology of PGX is to look at phenotypic responses to medication and then attempt to determine what gene or genes may be responsible Pharmacogenomics takes advantage of the fact that the entire human genome has now been sequenced. Pharmacogenomics looks at entire DNA sequences and attempts to identify those sequences that may influence drug metabolism. In genetic terms, PGX research reasons from phenotype to genotype, while pharmacogenetics reasons from genotype to phenotype. Many publications about genetic medicine use the terms Pharmocogenetics (PGX) and Pharmacogenomics–sometimes interchangably. What’s the Difference?

The short answer is that not everyone agrees on the distinction.

PGX came first and is generally understood to be the branch of pharmacology that studies individual genetically defined or modified responses to medications. The methodology of PGX is to look at phenotypic responses to medication and then attempt to determine what gene or genes may be responsible

Pharmacogenomics takes advantage of the fact that the entire human genome has now been sequenced. Pharmacogenomics looks at entire DNA sequences and attempts to identify those sequences that may influence drug metabolism.

In genetic terms, PGX research reasons from phenotype to genotype, while pharmacogenetics reasons from genotype to phenotype.

]]> by: doctore http://talk.genesanddrugs.com/2006/07/20/hello-world/#comment-4 Thu, 20 Jul 2006 18:34:27 +0000 http://talk.genesanddrugs.com/2006/07/20/hello-world/#comment-4 A good place to about pharmacogenetics and pharmacogenomics is in the <em>New England Journal of Medicine</em> 2002-3 series<a target="_blank" href="http://content.nejm.org/misc/genmed.shtml"> genetic medicine.</a> The NEJM Web site offers the full text at no charge. A good place to about pharmacogenetics and pharmacogenomics is in the New England Journal of Medicine 2002-3 series genetic medicine.

The NEJM Web site offers the full text at no charge.

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